CPA3

Across TCGA patient cohorts, CPA3 protein abundance is significantly associated with the RNA expression of many other genes, with 12,826 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CPA3-associated genes across cancer lineages are CTSG, SIGLEC6, and IL1RL1. Each is linked with CPA3 in more than 8 cancer types. Because this analysis shows association rather than direction, both CPA3-to-partner and partner-to-CPA3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CPA3 versus CTSG in BRCA, with a Pearson correlation of 0.74.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CPA3→partner) and Y-score (partner→CPA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CTSG →	+1.654	+1.283	<.001	<.001	3	9
LUAD	SIGLEC6 →	+0.755	+0.864	<.001	<.001	3	9
BRCA	IL1RL1 →	+0.980	+1.504	<.001	<.001	3	9
BRCA	HDC →	+1.341	+1.293	<.001	<.001	3	9
BRCA	MS4A2 →	+1.550	+1.277	<.001	<.001	3	9
CCRCC	EMCN →	+1.382	+0.631	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,826 associations by consensus.

CPA3 vs CTSG — BRCA

Explore this scatter interactively →