CPA3

Across TCGA cell cohorts, CPA3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,381 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CPA3-associated GO terms across cancer lineages are Actin filament fragmentation, Negative regulation of lysosome organization, and Protein myristoylation. Each is linked with CPA3 in more than 5 cancer types. Because this analysis shows association rather than direction, both CPA3-to-partner and partner-to-CPA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Actin filament fragmentation grouped by CPA3-low versus CPA3-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CPA3→partner) and Y-score (partner→CPA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Actin filament fragmentation →	+0.063	+0.710	.001	.008	3	5
CNS	Negative regulation of lysosome organization →	+0.051	+0.403	.004	.006	3	4
SOFT_TISSUE	Protein myristoylation →	+0.089	+0.949	<.001	.006	3	4
SOFT_TISSUE	Negative regulation of glycoprotein metabolic process →	+0.111	+0.976	<.001	.005	3	4
LUNG_SCLC	N-terminal protein amino acid modification →	+0.109	+0.101	.001	.009	1	6
SOFT_TISSUE	Maintenance of protein location in cell →	+0.114	+1.236	<.001	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,381 associations by consensus.

Actin filament fragmentation by CPA3 expression — CNS

Explore this box plot interactively →