CP

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CP RNA expression is significantly associated with the protein abundance of many other proteins, with 17,596 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CP-associated proteins across cancer lineages are SLC34A2, SLC16A3, and CEBPB. Each is linked with CP in more than 5 cancer types. Because this analysis shows association rather than direction, both CP-to-partner and partner-to-CP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CP versus SLC34A2 in BRCA, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CP→partner) and Y-score (partner→CP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCASLC34A2 →+1.367+2.798<.001<.00136
PDACSLC16A3 →+0.781+1.520<.001.00136
BRCACEBPB →+0.497+2.279<.001<.00136
GBMSMARCC2_S347 →-0.301-1.052.001.00835
CCRCCSTEAP3 →+0.650+1.674.001.00235
GBMSYTL3_S243 →+0.940+2.276<.001.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 17,596 associations by consensus.

CP vs SLC34A2 — BRCA

Per-sample scatter of CP vs SLC34A2 in BRCA (Pearson r = 0.49).

Explore this scatter interactively →

Exploration