CP

Across TCGA patient cohorts, CP protein abundance is significantly associated with the RNA expression of many other genes, with 14,669 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CP-associated genes across cancer lineages are FLT1, SEMA6B, and SLC2A3. Each is linked with CP in more than 6 cancer types. Because this analysis shows association rather than direction, both CP-to-partner and partner-to-CP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CP versus FLT1 in COAD, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CP→partner) and Y-score (partner→CP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	FLT1 →	+0.855	+0.625	<.001	.004	3	7
BRCA	SEMA6B →	+0.889	+0.559	<.001	<.001	3	7
COAD	SLC2A3 →	+1.513	+0.972	<.001	<.001	3	7
UCEC	FAM20A →	+1.045	+0.562	<.001	<.001	3	6
UCEC	ITGB3 →	+0.959	+0.484	.002	<.001	3	6
GBM	IRAK3 →	+1.010	+0.690	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,669 associations by consensus.

CP vs FLT1 — COAD

Explore this scatter interactively →