CP

Across TCGA cell cohorts, CP RNA expression is significantly associated with the go_rna of many other GO terms, with 2,736 significant associations in total. CNS shows the largest number of these associations.

The most reproducible CP-associated GO terms across cancer lineages are Fatty acid beta-oxidation, Isoprenoid catabolic process, and Biological process involved in interaction with host. Each is linked with CP in more than 7 cancer types. Because this analysis shows association rather than direction, both CP-to-partner and partner-to-CP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Fatty acid beta-oxidation grouped by CP-low versus CP-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CP→partner) and Y-score (partner→CP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Fatty acid beta-oxidation →	+0.087	+4.516	.001	<.001	3	7
LIVER	Isoprenoid catabolic process →	+1.786	+4.215	<.001	<.001	3	7
BREAST	Biological process involved in interaction with host →	+0.074	+2.281	<.001	.001	2	8
BREAST	Positive regulation of transcription initiation by RNA polymerase II →	+0.046	+1.611	.005	.009	2	8
CNS	Regulation of intracellular transport →	+0.050	+1.971	<.001	<.001	3	7
LIVER	Protein N-linked glycosylation →	+0.096	+5.545	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,736 associations by consensus.

Fatty acid beta-oxidation by CP expression — LIVER

Explore this box plot interactively →