Across TCGA pan-cancer cohorts, COX7BP2 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of COX7BP2’s most consistent transcriptional readouts.
The strongest signal is observed in colon adenocarcinoma (COAD), where COX7BP2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types COX7BP2 is over-expressed in tumor.
COAD and LUAD are the cancer types where COX7BP2 tumor–normal differential expression is most reproducible.