COX7B2

Across TCGA patient cohorts, COX7B2 mutation is significantly associated with the RNA expression of many other genes, with 133 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible COX7B2-associated genes across cancer lineages are RN7SKP169, MIR6858, and MLLT10P2. Each is linked with COX7B2 in more than 1 cancer types. Because this analysis shows association rather than direction, both COX7B2-to-partner and partner-to-COX7B2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP169 grouped by COX7B2-low versus COX7B2-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COX7B2→partner) and Y-score (partner→COX7B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RN7SKP169 →	+0.236	+5.182	<.001	.007	3	2
BLCA	MIR6858 →	+0.427	+3.799	.003	.007	3	2
UCEC	MLLT10P2 →	+0.218	+3.242	<.001	.007	3	2
BLCA	RSL24D1P4 →	+0.062	+5.722	<.001	.001	3	2
BLCA	RPS25P9 →	+0.286	+3.982	<.001	.006	3	2
BLCA	RPS23P7 →	+0.134	+3.982	.005	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 133 associations by consensus.

RN7SKP169 by COX7B2 expression — HNSC

Explore this box plot interactively →