COX7B2

Across TCGA patient cohorts, COX7B2 mutation is significantly associated with the total protein of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COX7B2-associated genes across cancer lineages are ERK2, G6PD, and NDRG1_pT346. Each is linked with COX7B2 in more than 1 cancer types. Because this analysis shows association rather than direction, both COX7B2-to-partner and partner-to-COX7B2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ERK2 grouped by COX7B2-low versus COX7B2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COX7B2→partner) and Y-score (partner→COX7B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ERK2 →	+0.349	+3.000	.001	.037	3	1
UCEC	G6PD →	+0.477	+3.000	.010	.037	3	1
UCEC	NDRG1_pT346 →	-0.600	-3.000	.034	.037	3	1
UCEC	p70-S6K_pT389 →	-0.222	-3.000	.043	.037	3	1
UCEC	Annexin-1 →	+0.730	+3.000	.016	.037	3	1
UCEC	Caspase-7-cleavedD198 →	+0.740	+3.000	.031	.037	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

ERK2 by COX7B2 expression — UCEC

Explore this box plot interactively →