COX7B

Across TCGA pan-cancer cohorts, COX7B mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated COX7B data layer compared with 26 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher COX7B mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated COX7B expression acts as an unfavorable survival marker, although some lineages such as CCRCC and COAD show a favorable association.

CCRCC, COAD, and HNSC are the cancer types where COX7B mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Tertile	All	1.000	0.526	.002	15	view →
COAD	DFS	Median	All	1.000	0.919	.013	12	view →
HNSC	OS	Median	II,III,IV	0.818	0.633	.012	12	view →
LUAD	OS	Median	III,IV	0.226	0.614	.023	5	view →
LSCC	DFS	Tertile	II,III,IV	1.000	0.832	.017	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

COX7B–CCRCC (DFS)

Open the CCRCC breakdown →