COX7B

Across TCGA patient cohorts, COX7B mutation is significantly associated with the RNA expression of many other genes, with 373 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COX7B-associated genes across cancer lineages are UBL5P3, NUTF2P8, and RPS28P1. Each is linked with COX7B in more than 1 cancer types. Because this analysis shows association rather than direction, both COX7B-to-partner and partner-to-COX7B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UBL5P3 grouped by COX7B-low versus COX7B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COX7B→partner) and Y-score (partner→COX7B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	UBL5P3 →	+0.164	+2.963	.001	.003	3	2
UCEC	NUTF2P8 →	+0.135	+2.813	<.001	.005	3	1
UCEC	RPS28P1 →	+0.212	+3.290	<.001	.005	3	1
UCEC	KRT18P9 →	+0.178	+2.477	.006	.008	3	1
UCEC	HMGB1P50 →	+0.144	+2.191	.009	.008	3	1
UCEC	NIPA2P3 →	+0.077	+4.412	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 373 associations by consensus.

UBL5P3 by COX7B expression — UCEC

Explore this box plot interactively →