COX7A2L

Across TCGA cell cohorts, COX7A2L RNA expression is significantly associated with the go_rna of many other GO terms, with 2,782 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible COX7A2L-associated GO terms across cancer lineages are DNA replication proofreading, Actomyosin contractile ring organization, and Actomyosin contractile ring assembly actin filament organization. Each is linked with COX7A2L in more than 9 cancer types. Because this analysis shows association rather than direction, both COX7A2L-to-partner and partner-to-COX7A2L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication proofreading grouped by COX7A2L-low versus COX7A2L-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COX7A2L→partner) and Y-score (partner→COX7A2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	DNA replication proofreading →	-0.194	-0.843	<.001	<.001	3	10
BREAST	Actomyosin contractile ring organization →	-0.136	-0.566	.001	.003	3	10
PANCREAS	Actomyosin contractile ring assembly actin filament organization →	-0.133	-0.590	<.001	<.001	3	9
KIDNEY	Hemidesmosome assembly →	-0.187	-0.589	.004	.002	3	9
BREAST	Positive regulation of protein import into nucleus →	-0.086	-0.514	<.001	.001	3	9
BREAST	Assembly of actomyosin apparatus involved in cytokinesis →	-0.202	-0.582	<.001	.005	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,782 associations by consensus.

DNA replication proofreading by COX7A2L expression — OESOPHAGUS

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