COX6CP8

Across TCGA pan-cancer cohorts, COX6CP8 RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated COX6CP8 data layer.

The strongest signal is observed in testicular germ cell tumors (TGCT), where higher COX6CP8 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated COX6CP8 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

TGCT, OV, and SKCM are the cancer types where COX6CP8 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
TGCT	OS	Tertile	II,III,IV	0.501	0.996	<.001	90	view →
OV	OS	Tertile	IV	0.022	0.760	<.001	54	view →
SKCM	OS	Tertile	All	0.197	0.873	<.001	36	view →
SARC	OS	Tertile	All	0.022	0.861	<.001	36	view →
LIHC	DFS	Tertile	All	0.068	0.555	<.001	36	view →
STAD	OS	Tertile	III,IV	0.277	0.648	.021	27	view →
UCS	OS	Tertile	All	0.153	0.687	.019	18	view →
HNSC	OS	Tertile	All	1.000	0.676	.038	6	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

COX6CP8–TGCT (OS)

Open the TGCT breakdown →