COX6CP12

Across TCGA pan-cancer cohorts, COX6CP12 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated COX6CP12 data layer.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher COX6CP12 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated COX6CP12 expression acts as an unfavorable survival marker, although some lineages such as HNSC and SARC show a favorable association.

READ, SKCM, and BRCA are the cancer types where COX6CP12 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	DFS	Tertile	All	0.157	0.853	<.001	45	view →
SKCM	OS	Tertile	All	0.131	0.351	<.001	36	view →
BRCA	DFS	Tertile	All	0.570	1.000	.033	36	view →
LGG	DFS	Tertile	All	0.237	0.736	<.001	30	view →
KIRC	DFS	Tertile	II,III,IV	0.251	0.666	.009	24	view →
ESCA	DFS	Tertile	All	0.264	0.517	.011	18	view →
TGCT	DFS	Tertile	All	0.076	0.801	.001	18	view →
UCS	DFS	Tertile	All	0.202	0.535	.044	18	view →
STAD	DFS	Tertile	III,IV	0.218	0.501	.040	9	view →
LUSC	DFS	Tertile	II,III,IV	0.135	0.663	.015	9	view →
OV	OS	Tertile	III,IV	0.740	0.842	.045	6	view →
HNSC	DFS	Tertile	All	0.822	0.315	.049	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

COX6CP12–READ (DFS)

Open the READ breakdown →