COX6C

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, COX6C protein abundance is significantly associated with the RNA expression of many other genes, with 11,922 significant associations in total. OV shows the largest number of these associations.

The most reproducible COX6C-associated genes across cancer lineages are KIRREL1, SYDE1, and PCOLCE. Each is linked with COX6C in more than 5 cancer types. Because this analysis shows association rather than direction, both COX6C-to-partner and partner-to-COX6C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COX6C versus KIRREL1 in OV, with a Pearson correlation of -0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COX6C→partner) and Y-score (partner→COX6C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVKIRREL1 →-1.084-0.566<.001<.00136
OVSYDE1 →-1.057-0.494<.001<.00135
OVPCOLCE →-1.537-0.566<.001<.00135
OVLTBP2 →-1.346-0.494<.001.00135
OVEMILIN1 →-1.371-0.534<.001<.00135
OVRCN3 →-1.323-0.521<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,922 associations by consensus.

COX6C vs KIRREL1 — OV

Per-sample scatter of COX6C vs KIRREL1 in OV (Pearson r = -0.37).

Explore this scatter interactively →

Exploration