COX6C

Across TCGA cell cohorts, COX6C RNA expression is significantly associated with the go_rna of many other GO terms, with 4,008 significant associations in total. BONE shows the largest number of these associations.

The most reproducible COX6C-associated GO terms across cancer lineages are Regulation of fibroblast proliferation, Regulation of cell morphogenesis, and Regulation of cell-substrate junction organization. Each is linked with COX6C in more than 10 cancer types. Because this analysis shows association rather than direction, both COX6C-to-partner and partner-to-COX6C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of fibroblast proliferation grouped by COX6C-low versus COX6C-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COX6C→partner) and Y-score (partner→COX6C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of fibroblast proliferation →	-0.088	-1.058	.003	.001	3	11
LARGE_INTESTINE	Regulation of cell morphogenesis →	-0.056	-0.808	<.001	.001	3	11
BONE	Regulation of cell-substrate junction organization →	-0.161	-0.923	<.001	.001	3	11
BONE	Regulation of focal adhesion assembly →	-0.171	-0.864	<.001	.001	3	10
BONE	Regulation of cell-substrate junction assembly →	-0.171	-0.864	<.001	.001	3	10
BREAST	Cell-substrate junction organization →	-0.187	-1.530	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,008 associations by consensus.

Regulation of fibroblast proliferation by COX6C expression — OESOPHAGUS

Explore this box plot interactively →