COX6B2

Across TCGA patient cohorts, COX6B2 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,124 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible COX6B2-associated GO terms across cancer lineages are Amyloid precursor protein metabolic process, Amyloid precursor protein catabolic process, and Protein hydroxylation. Each is linked with COX6B2 in more than 21 cancer types. Because this analysis shows association rather than direction, both COX6B2-to-partner and partner-to-COX6B2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Amyloid precursor protein metabolic process grouped by COX6B2-low versus COX6B2-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COX6B2→partner) and Y-score (partner→COX6B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Amyloid precursor protein metabolic process →	+0.041	+0.907	<.001	<.001	3	21
LAML	Amyloid precursor protein catabolic process →	+0.048	+0.300	<.001	.001	2	22
PAAD	Protein hydroxylation →	+0.043	+1.287	<.001	<.001	3	20
STAD	Placenta development →	+0.030	+0.387	<.001	<.001	3	20
STAD	Embryonic placenta development →	+0.039	+0.573	<.001	<.001	3	20
ESCA	Collagen metabolic process →	+0.059	+0.931	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,124 associations by consensus.

Amyloid precursor protein metabolic process by COX6B2 expression — ESCA

Explore this box plot interactively →