COX6B1P5

Across TCGA pan-cancer cohorts, COX6B1P5 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated COX6B1P5 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher COX6B1P5 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated COX6B1P5 expression acts as an unfavorable survival marker, although some lineages such as GBM and UCS show a favorable association.

UVM, COAD, and GBM are the cancer types where COX6B1P5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Median	III,IV	0.312	0.726	<.001	85	view →
COAD	DFS	Tertile	All	0.438	0.724	.006	33	view →
GBM	DFS	Tertile	All	0.325	0.178	.003	22	view →
LGG	DFS	Tertile	All	0.375	0.550	<.001	21	view →
UCS	OS	Tertile	IV	0.883	0.346	.024	18	view →
SARC	OS	Quartile	All	0.427	0.717	.006	14	view →
STAD	DFS	Tertile	IV	0.245	0.777	.013	12	view →
ESCA	DFS	Quartile	All	1.000	0.429	.018	12	view →
OV	DFS	Quartile	IV	0.254	0.469	.030	10	view →
PAAD	DFS	Median	III,IV	0.370	0.853	.010	9	view →
HNSC	OS	Median	II,III,IV	0.498	0.309	.012	9	view →
BRCA	OS	Quartile	III,IV	0.958	0.837	.008	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

COX6B1P5–UVM (DFS)

Open the UVM breakdown →