COX6B1

Across TCGA patient cohorts, COX6B1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,258 significant associations in total. GBM shows the largest number of these associations.

The most reproducible COX6B1-associated genes across cancer lineages are MXD1, HIF1A, and AQP9. Each is linked with COX6B1 in more than 5 cancer types. Because this analysis shows association rather than direction, both COX6B1-to-partner and partner-to-COX6B1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COX6B1 versus MXD1 in OV, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COX6B1→partner) and Y-score (partner→COX6B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MXD1 →	-0.671	-0.424	.006	.004	3	6
OV	HIF1A →	-0.566	-0.369	.002	.002	3	4
COAD	AQP9 →	-1.181	-0.404	<.001	<.001	3	4
COAD	SSR3 →	-0.415	-0.392	.003	.002	3	4
HNSC	RLF →	-0.674	-0.380	<.001	<.001	3	4
LUAD	CENPL →	-0.595	-0.256	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,258 associations by consensus.

COX6B1 vs MXD1 — OV

Explore this scatter interactively →