COX6B1

Across TCGA cell cohorts, COX6B1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,333 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible COX6B1-associated GO terms across cancer lineages are Positive regulation of endopeptidase activity, Mitochondrial respiratory chain complex assembly, and [2Fe-2S] cluster assembly. Each is linked with COX6B1 in more than 12 cancer types. Because this analysis shows association rather than direction, both COX6B1-to-partner and partner-to-COX6B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of endopeptidase activity grouped by COX6B1-low versus COX6B1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COX6B1→partner) and Y-score (partner→COX6B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of endopeptidase activity →	+0.213	+0.939	<.001	<.001	3	12
BONE	Mitochondrial respiratory chain complex assembly →	+0.082	+0.915	.006	.003	2	13
BONE	[2Fe-2S] cluster assembly →	+0.152	+1.168	.001	<.001	3	12
BONE	Pre-mRNA catabolic process →	-0.240	-0.868	<.001	.001	3	11
BONE	Mitochondrial translation →	+0.085	+0.824	.005	.004	2	12
BONE	Regulation of centriole-centriole cohesion →	-0.130	-0.719	<.001	.007	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,333 associations by consensus.

Positive regulation of endopeptidase activity by COX6B1 expression — BONE

Explore this box plot interactively →