Across TCGA pan-cancer cohorts, COX6A1P3 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of COX6A1P3’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where COX6A1P3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types COX6A1P3 is over-expressed in tumor.

BLCA and LUSC are the cancer types where COX6A1P3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in COX6A1P3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	All	III,IV	+0.072	.034	3	view →
LUSC	All	II,III,IV	+0.046	.042	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: COX6A1P3 RNA expression & survival · all COX6A1P3 data types