COX6A1

Across TCGA patient cohorts, COX6A1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,661 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible COX6A1-associated genes across cancer lineages are ADAM17, ARL13B, and DUSP12. Each is linked with COX6A1 in more than 4 cancer types. Because this analysis shows association rather than direction, both COX6A1-to-partner and partner-to-COX6A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COX6A1 versus ADAM17 in LSCC, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COX6A1→partner) and Y-score (partner→COX6A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ADAM17 →	-0.544	-0.205	<.001	.001	3	5
LSCC	ARL13B →	-0.387	-0.177	.001	<.001	3	5
LSCC	DUSP12 →	-0.454	-0.256	<.001	<.001	3	5
LSCC	RAD1 →	-0.501	-0.250	<.001	<.001	3	4
LSCC	MSH6 →	-0.619	-0.201	<.001	<.001	3	4
LSCC	FARSB →	-0.448	-0.247	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,661 associations by consensus.

COX6A1 vs ADAM17 — LSCC

Explore this scatter interactively →