COX6A1

Across TCGA cell cohorts, COX6A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,572 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible COX6A1-associated GO terms across cancer lineages are Regulation of cell-substrate junction assembly, Regulation of focal adhesion assembly, and Regulation of cell-matrix adhesion. Each is linked with COX6A1 in more than 12 cancer types. Because this analysis shows association rather than direction, both COX6A1-to-partner and partner-to-COX6A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cell-substrate junction assembly grouped by COX6A1-low versus COX6A1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COX6A1→partner) and Y-score (partner→COX6A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of cell-substrate junction assembly →	-0.149	-0.533	<.001	<.001	3	13
BONE	Regulation of focal adhesion assembly →	-0.149	-0.533	<.001	<.001	3	13
BONE	Regulation of cell-matrix adhesion →	-0.173	-0.735	<.001	<.001	3	12
BONE	Positive regulation of focal adhesion assembly →	-0.185	-0.622	<.001	<.001	3	12
BONE	Regulation of cell-substrate adhesion →	-0.134	-0.837	<.001	<.001	3	11
BONE	Regulation of cell-substrate junction organization →	-0.184	-0.865	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,572 associations by consensus.

Regulation of cell-substrate junction assembly by COX6A1 expression — BONE

Explore this box plot interactively →