COX5BP4

Across TCGA pan-cancer cohorts, COX5BP4 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated COX5BP4 data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher COX5BP4 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated COX5BP4 expression acts as an unfavorable survival marker, although some lineages such as BLCA and KIRC show a favorable association.

LUAD, MESO, and BLCA are the cancer types where COX5BP4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Quartile	All	0.792	0.945	<.001	58	view →
MESO	OS	Tertile	All	0.250	0.465	.001	57	view →
BLCA	OS	Quartile	All	0.791	0.652	.001	55	view →
UCEC	DFS	Quartile	All	0.483	0.726	<.001	40	view →
KIRP	OS	Quartile	All	0.837	0.965	<.001	38	view →
COAD	DFS	Tertile	All	0.423	0.659	.003	23	view →
KIRC	DFS	Tertile	IV	0.711	0.234	.005	18	view →
LAML	DFS	Tertile	All	0.582	0.287	.019	12	view →
PRAD	DFS	Median	All	0.849	0.921	.009	10	view →
OV	DFS	Quartile	II,III,IV	0.305	0.385	.036	8	view →
READ	OS	Median	II,III,IV	0.984	0.849	.022	7	view →
LIHC	OS	Quartile	All	0.475	0.604	.032	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

COX5BP4–LUAD (OS)

Open the LUAD breakdown →