COX5AP1

Across TCGA pan-cancer cohorts, COX5AP1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated COX5AP1 data layer.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher COX5AP1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated COX5AP1 expression acts as an unfavorable survival marker, although some lineages such as READ and LIHC show a favorable association.

READ, LIHC, and ACC are the cancer types where COX5AP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	DFS	Tertile	All	0.748	0.402	.001	37	view →
LIHC	OS	Tertile	II,III,IV	0.860	0.317	<.001	36	view →
ACC	OS	Tertile	All	0.398	0.825	.010	28	view →
CHOL	DFS	Tertile	All	0.097	0.482	.020	24	view →
PAAD	DFS	Tertile	All	0.493	0.277	.016	21	view →
OV	DFS	Median	All	0.433	0.331	.002	18	view →
MESO	OS	Tertile	III,IV	0.359	0.609	.003	18	view →
UCS	OS	Median	All	0.215	0.523	.006	18	view →
COAD	DFS	Tertile	All	0.849	0.727	.021	10	view →
SARC	DFS	Median	All	0.244	0.413	.002	10	view →
DLBC	DFS	Quartile	II,III,IV	0.143	0.863	.018	6	view →
KIRP	OS	Tertile	II,III,IV	0.934	0.766	.022	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

COX5AP1–READ (DFS)

Open the READ breakdown →