COX5A

Across TCGA patient cohorts, COX5A protein abundance is significantly associated with the RNA expression of many other genes, with 11,346 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible COX5A-associated genes across cancer lineages are PDLIM3, CCDC80, and TREM1. Each is linked with COX5A in more than 5 cancer types. Because this analysis shows association rather than direction, both COX5A-to-partner and partner-to-COX5A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COX5A versus PDLIM3 in UCEC, with a Pearson correlation of -0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COX5A→partner) and Y-score (partner→COX5A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PDLIM3 →	-1.099	-0.353	.004	<.001	3	6
OV	CCDC80 →	-1.509	-0.449	.001	.006	3	6
LSCC	TREM1 →	-0.922	-0.305	<.001	<.001	3	5
COAD	SLC11A1 →	-1.245	-0.397	<.001	<.001	3	5
COAD	C5AR1 →	-1.131	-0.415	<.001	<.001	3	5
UCEC	CNRIP1 →	-0.826	-0.424	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,346 associations by consensus.

COX5A vs PDLIM3 — UCEC

Explore this scatter interactively →