COX5A

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, COX5A mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COX5A-associated genes across cancer lineages are Hepatocytes and Pericytes. Each is linked with COX5A in more than 1 cancer types. Because this analysis shows association rather than direction, both COX5A-to-partner and partner-to-COX5A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Hepatocytes grouped by COX5A-low versus COX5A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COX5A→partner) and Y-score (partner→COX5A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECHepatocytes →+0.019+2.828.002.03631
UCECPericytes →+0.037+2.113.023.04431
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Hepatocytes by COX5A expression — UCEC

Box plot of Hepatocytes in COX5A-low vs COX5A-high samples in UCEC.

Explore this box plot interactively →

Exploration