COX5A

Across TCGA cell cohorts, COX5A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,663 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible COX5A-associated GO terms across cancer lineages are Ubiquinone metabolic process, Quinone metabolic process, and Ketone metabolic process. Each is linked with COX5A in more than 13 cancer types. Because this analysis shows association rather than direction, both COX5A-to-partner and partner-to-COX5A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ubiquinone metabolic process grouped by COX5A-low versus COX5A-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COX5A→partner) and Y-score (partner→COX5A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Ubiquinone metabolic process →	+0.109	+1.129	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Quinone metabolic process →	+0.108	+1.086	<.001	<.001	3	13
LUNG_NSCLC_LUSC	Ketone metabolic process →	+0.114	+0.707	<.001	.002	2	14
UPPER_AERODIGESTIVE_TRACT	Quinone biosynthetic process →	+0.098	+0.992	<.001	<.001	3	12
BONE	Mitochondrial translation →	+0.116	+0.647	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Mitochondrial respiratory chain complex assembly →	+0.088	+0.907	<.001	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,663 associations by consensus.

Ubiquinone metabolic process by COX5A expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →