COX4I1

Across TCGA patient cohorts, COX4I1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,919 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible COX4I1-associated proteins across cancer lineages are KARS1, AP1G1, and MTHFSD. Each is linked with COX4I1 in more than 5 cancer types. Because this analysis shows association rather than direction, both COX4I1-to-partner and partner-to-COX4I1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COX4I1 versus KARS1 in OV, with a Pearson correlation of 0.61.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COX4I1→partner) and Y-score (partner→COX4I1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	KARS1 →	+0.351	+0.570	<.001	<.001	3	6
CCRCC	AP1G1 →	+0.231	+0.368	<.001	<.001	3	5
OV	MTHFSD →	+0.341	+0.580	.001	.003	3	5
BRCA	MVD →	+0.402	+0.269	<.001	.005	3	5
GBM	HSDL1 →	+0.488	+0.298	<.001	<.001	3	5
LSCC	CMIP →	+0.515	+0.545	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,919 associations by consensus.

COX4I1 vs KARS1 — OV

Explore this scatter interactively →