COX4I1

Across TCGA cell cohorts, COX4I1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,099 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible COX4I1-associated GO terms across cancer lineages are Mitochondrial translation, tRNA thio-modification, and Modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration. Each is linked with COX4I1 in more than 10 cancer types. Because this analysis shows association rather than direction, both COX4I1-to-partner and partner-to-COX4I1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial translation grouped by COX4I1-low versus COX4I1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COX4I1→partner) and Y-score (partner→COX4I1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Mitochondrial translation →	+0.097	+0.935	<.001	<.001	3	11
BREAST	tRNA thio-modification →	+0.117	+0.866	<.001	<.001	3	11
LARGE_INTESTINE	Modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration →	-0.166	-0.703	<.001	<.001	3	10
LARGE_INTESTINE	Succinyl-CoA metabolic process →	+0.111	+0.644	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	miRNA metabolic process →	-0.127	-0.890	.001	.003	3	9
LUNG_SCLC	Propionyl-CoA metabolic process →	+0.144	+0.656	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,099 associations by consensus.

Mitochondrial translation by COX4I1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →