COX20P2

Across TCGA pan-cancer cohorts, COX20P2 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated COX20P2 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher COX20P2 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated COX20P2 expression acts as an unfavorable survival marker, although some lineages such as KIRC and HNSC show a favorable association.

KIRC, HNSC, and LGG are the cancer types where COX20P2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	II,III,IV	0.861	0.734	.001	114	view →
HNSC	DFS	Quartile	III,IV	0.448	0.258	<.001	106	view →
LGG	DFS	Median	All	0.650	0.824	<.001	54	view →
LUAD	DFS	Quartile	III,IV	0.258	0.489	.006	45	view →
LIHC	OS	Tertile	II,III,IV	0.403	0.669	.001	33	view →
MESO	OS	Tertile	IV	0.243	0.648	.010	27	view →
UCS	DFS	Median	II,III,IV	0.620	0.311	.016	24	view →
KICH	OS	Tertile	III,IV	0.178	0.847	<.001	18	view →
CHOL	OS	Tertile	II,III,IV	0.019	0.765	.001	18	view →
ACC	OS	Tertile	IV	0.327	0.633	.045	18	view →
UVM	OS	Tertile	All	0.383	0.734	.046	12	view →
LUSC	DFS	Tertile	II,III,IV	0.611	0.755	.011	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

COX20P2–KIRC (DFS)

Open the KIRC breakdown →