Across TCGA patient cohorts, COX20 protein abundance is significantly associated with the RNA expression of many other genes, with 14,002 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible COX20-associated genes across cancer lineages are CXorf21, ITM2A, and ATP8B4. Each is linked with COX20 in more than 6 cancer types. Because this analysis shows association rather than direction, both COX20-to-partner and partner-to-COX20 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COX20→partner) and Y-score (partner→COX20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CXorf21 →	-0.803	-0.309	.003	.007	2	7
BRCA	ITM2A →	-1.090	-0.428	<.001	<.001	3	6
HNSC	ATP8B4 →	-0.837	-0.502	<.001	<.001	3	5
HNSC	PIK3CG →	-0.859	-0.355	<.001	<.001	2	6
LSCC	TFEC →	-0.787	-0.436	<.001	<.001	3	5
OV	SFRP4 →	-1.937	-0.388	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,002 associations by consensus.

Exploration

COX20 survival (RNA) · tumor vs normal (RNA) · all COX20 data types