Across TCGA patient cohorts, COX20 mutation is significantly associated with the total protein of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COX20-associated genes across cancer lineages are EGFR_pY1173, GATA6, and mTOR_pS2448. Each is linked with COX20 in more than 1 cancer types. Because this analysis shows association rather than direction, both COX20-to-partner and partner-to-COX20 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COX20→partner) and Y-score (partner→COX20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1173 →	+0.092	+2.026	.010	.018	3	1
UCEC	GATA6 →	-0.158	-2.985	.028	.034	3	1
UCEC	mTOR_pS2448 →	-0.178	-2.000	.008	.032	3	1
UCEC	p38-MAPK_pT180_Y182 →	-0.498	-2.321	.014	.034	3	1
UCEC	PDCD4 →	-0.527	-2.000	.013	.032	3	1
UCEC	Rab11 →	-0.129	-3.169	.048	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

Exploration

COX20 survival (RNA) · tumor vs normal (RNA) · all COX20 data types