COX18

Across TCGA cell cohorts, COX18 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,418 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible COX18-associated GO terms across cancer lineages are Mitochondrial ribosome assembly, Protein deneddylation, and Positive regulation of isotype switching to IgG isotypes. Each is linked with COX18 in more than 9 cancer types. Because this analysis shows association rather than direction, both COX18-to-partner and partner-to-COX18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial ribosome assembly grouped by COX18-low versus COX18-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COX18→partner) and Y-score (partner→COX18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Mitochondrial ribosome assembly →	+0.061	+0.577	<.001	<.001	3	10
PANCREAS	Protein deneddylation →	+0.097	+0.552	.001	.002	3	10
SKIN	Positive regulation of isotype switching to IgG isotypes →	+0.129	+0.524	<.001	.001	3	9
BONE	Copper ion export →	-0.200	-0.849	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	DNA damage tolerance →	+0.070	+0.641	.003	.003	3	9
SOFT_TISSUE	Negative regulation of chromosome condensation →	+0.164	+0.701	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,418 associations by consensus.

Mitochondrial ribosome assembly by COX18 expression — LARGE_INTESTINE

Explore this box plot interactively →