COX16

Across TCGA patient cohorts, COX16 protein abundance is significantly associated with the RNA expression of many other genes, with 549 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible COX16-associated genes across cancer lineages are RNA5SP90, PLA2G3, and GSDME. Each is linked with COX16 in more than 1 cancer types. Because this analysis shows association rather than direction, both COX16-to-partner and partner-to-COX16 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COX16 versus RNA5SP90 in CCRCC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COX16→partner) and Y-score (partner→COX16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	RNA5SP90 →	+1.127	+0.294	.001	.004	3	2
GBM	PLA2G3 →	-0.233	-0.378	.001	.004	3	1
GBM	GSDME →	+1.211	+0.511	.003	<.001	3	1
GBM	SPATA6L →	-0.851	-0.652	<.001	.002	3	1
GBM	H3-3B →	+0.533	+0.385	.005	.007	3	1
GBM	PPIAP26 →	-0.270	-0.489	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 549 associations by consensus.

COX16 vs RNA5SP90 — CCRCC

Explore this scatter interactively →