COX15

Across TCGA patient cohorts, COX15 mutation is significantly associated with the RNA expression of many other genes, with 102 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COX15-associated genes across cancer lineages are MRGPRX9P, RNA5SP360, and TUBBP11. Each is linked with COX15 in more than 1 cancer types. Because this analysis shows association rather than direction, both COX15-to-partner and partner-to-COX15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MRGPRX9P grouped by COX15-low versus COX15-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COX15→partner) and Y-score (partner→COX15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MRGPRX9P →	+0.052	+4.743	<.001	.005	3	2
BRCA	RNA5SP360 →	+0.463	+8.243	<.001	<.001	3	2
BRCA	TUBBP11 →	+0.310	+6.786	<.001	<.001	3	2
UCEC	RNA5SP411 →	+1.541	+2.978	<.001	.001	3	2
UCEC	RNU6-1318P →	+0.559	+3.773	<.001	<.001	3	2
BRCA	MIR6853 →	+0.242	+8.057	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 102 associations by consensus.

MRGPRX9P by COX15 expression — SKCM

Explore this box plot interactively →