COX15

Across TCGA patient cohorts, COX15 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COX15-associated genes across cancer lineages are Adipocytes, CD8+ T-cells, and Endothelial cells. Each is linked with COX15 in more than 1 cancer types. Because this analysis shows association rather than direction, both COX15-to-partner and partner-to-COX15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Adipocytes grouped by COX15-low versus COX15-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COX15→partner) and Y-score (partner→COX15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Adipocytes →	+0.023	+2.507	.019	.022	3	2
PRAD	CD8+ T-cells →	+0.039	+5.453	<.001	.044	3	1
UCEC	Endothelial cells →	-0.043	-3.127	.041	.020	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Adipocytes by COX15 expression — UCEC

Explore this box plot interactively →