COX14

Across TCGA cell cohorts, COX14 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,735 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible COX14-associated GO terms across cancer lineages are Cell-substrate adhesion, Iron-sulfur cluster assembly, and Metallo-sulfur cluster assembly. Each is linked with COX14 in more than 8 cancer types. Because this analysis shows association rather than direction, both COX14-to-partner and partner-to-COX14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cell-substrate adhesion grouped by COX14-low versus COX14-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COX14→partner) and Y-score (partner→COX14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Cell-substrate adhesion →	-0.085	-0.708	<.001	<.001	3	8
BONE	Iron-sulfur cluster assembly →	+0.091	+0.435	.006	.007	1	9
BONE	Metallo-sulfur cluster assembly →	+0.091	+0.435	.006	.007	1	9
LUNG_NSCLC_LUAD	Dolichol phosphate mannose biosynthetic process →	+0.076	+0.579	<.001	.005	2	8
BONE	Regulation of mesenchymal cell proliferation →	-0.133	-0.534	.001	<.001	3	7
LUNG_SCLC	Positive regulation of epithelial to mesenchymal transition →	-0.098	-0.438	.008	.009	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,735 associations by consensus.

Cell-substrate adhesion by COX14 expression — BREAST

Explore this box plot interactively →