COX14

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, COX14 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible COX14-associated genes across cancer lineages are MYF6 and OR1L6. Each is linked with COX14 in more than 1 cancer types. Because this analysis shows association rather than direction, both COX14-to-partner and partner-to-COX14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYF6 grouped by COX14-low versus COX14-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COX14→partner) and Y-score (partner→COX14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEMYF6 →+0.014+4.415<.001.00731
LARGE_INTESTINEOR1L6 →+0.027+5.022<.001.00231
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

MYF6 by COX14 expression — LARGE_INTESTINE

Box plot of MYF6 in COX14-low vs COX14-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration