CORO7

Across TCGA pan-cancer cohorts, CORO7 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated CORO7 data layer compared with 24 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher CORO7 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated CORO7 expression acts as an unfavorable survival marker, although some lineages such as LSCC and UCEC show a favorable association.

PDAC, LSCC, and CCRCC are the cancer types where CORO7 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Tertile	IV	0.231	0.934	.024	12	view →
LSCC	DFS	Tertile	All	0.911	0.327	.019	10	view →
CCRCC	DFS	Tertile	All	0.411	0.873	.009	8	view →
LUAD	OS	Tertile	All	0.816	1.000	.013	6	view →
UCEC	OS	Median	II,III,IV	1.000	0.671	.029	4	view →
HNSC	DFS	Quartile	III,IV	1.000	0.504	.005	4	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

CORO7–PDAC (DFS)

Open the PDAC breakdown →