CORO7

Across TCGA patient cohorts, CORO7 mutation is significantly associated with the RNA expression of many other genes, with 5,853 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CORO7-associated genes across cancer lineages are LCEP1, MIR370, and RN7SL352P. Each is linked with CORO7 in more than 2 cancer types. Because this analysis shows association rather than direction, both CORO7-to-partner and partner-to-CORO7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LCEP1 grouped by CORO7-low versus CORO7-high in PRAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CORO7→partner) and Y-score (partner→CORO7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PRAD	LCEP1 →	+0.213	+7.939	<.001	.008	3	3
LUSC	MIR370 →	+0.217	+3.337	.003	.006	3	3
SKCM	RN7SL352P →	+0.077	+4.054	<.001	.001	3	3
SKCM	RNU6-982P →	+0.149	+3.555	<.001	.003	3	3
UCEC	RNU1-17P →	+0.152	+1.836	<.001	.004	3	3
UCEC	ASAH2B →	+0.288	+1.701	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,853 associations by consensus.

LCEP1 by CORO7 expression — PRAD

Explore this box plot interactively →