CORO7

Across TCGA cell cohorts, CORO7 mutation is significantly associated with the RNA expression of many other genes, with 43 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CORO7-associated genes across cancer lineages are IQCF5, OR5P2, and FCN2. Each is linked with CORO7 in more than 1 cancer types. Because this analysis shows association rather than direction, both CORO7-to-partner and partner-to-CORO7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IQCF5 grouped by CORO7-low versus CORO7-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CORO7→partner) and Y-score (partner→CORO7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	IQCF5 →	+0.060	+4.977	<.001	.002	3	2
BLOOD_Lymphoma	OR5P2 →	+0.028	+4.867	<.001	.009	3	2
LARGE_INTESTINE	FCN2 →	+0.025	+3.678	<.001	.001	3	2
SOFT_TISSUE	CST9L →	+0.021	+4.369	<.001	.008	3	1
SOFT_TISSUE	SMCP →	+0.101	+4.369	<.001	.008	3	1
SOFT_TISSUE	FCRL4 →	+0.010	+4.977	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 43 associations by consensus.

IQCF5 by CORO7 expression — SOFT_TISSUE

Explore this box plot interactively →