CORO6

Across TCGA cell cohorts, CORO6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,066 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CORO6-associated GO terms across cancer lineages are Regulation of hematopoietic stem cell differentiation, mRNA transport, and Establishment of RNA localization. Each is linked with CORO6 in more than 7 cancer types. Because this analysis shows association rather than direction, both CORO6-to-partner and partner-to-CORO6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of hematopoietic stem cell differentiation grouped by CORO6-low versus CORO6-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CORO6→partner) and Y-score (partner→CORO6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Regulation of hematopoietic stem cell differentiation →	+0.085	+1.030	<.001	<.001	3	8
LARGE_INTESTINE	mRNA transport →	+0.074	+0.974	<.001	.001	3	8
LARGE_INTESTINE	Establishment of RNA localization →	+0.068	+0.730	<.001	.001	3	8
LARGE_INTESTINE	RNA localization →	+0.074	+0.855	<.001	<.001	3	8
LARGE_INTESTINE	Positive regulation of DNA-templated transcription initiation →	+0.052	+0.696	<.001	.002	3	7
KIDNEY	Elastin metabolic process →	+0.219	+2.175	.004	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,066 associations by consensus.

Regulation of hematopoietic stem cell differentiation by CORO6 expression — LARGE_INTESTINE

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