CORO6

Across TCGA cell cohorts, CORO6 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CORO6-associated genes across cancer lineages are TSPY2, TECRL, and OR6Q1. Each is linked with CORO6 in more than 1 cancer types. Because this analysis shows association rather than direction, both CORO6-to-partner and partner-to-CORO6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TSPY2 grouped by CORO6-low versus CORO6-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CORO6→partner) and Y-score (partner→CORO6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TSPY2 →	+0.044	+3.217	<.001	.006	3	1
LARGE_INTESTINE	TECRL →	+0.012	+3.562	<.001	.002	3	1
LARGE_INTESTINE	OR6Q1 →	+0.012	+3.700	<.001	.009	3	1
LARGE_INTESTINE	AMELY →	+0.025	+3.700	<.001	.009	3	1
BLOOD_Leukemia	ASZ1 →	+0.119	+4.152	.001	.009	3	1
BLOOD_Leukemia	CST2 →	+0.499	+4.152	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

TSPY2 by CORO6 expression — LARGE_INTESTINE

Explore this box plot interactively →