CORO2A

Across TCGA pan-cancer cohorts, CORO2A mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated CORO2A data layer compared with 22 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher CORO2A mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated CORO2A expression acts as an unfavorable survival marker, although some lineages such as COAD and PDAC show a favorable association.

COAD, PDAC, and UCEC are the cancer types where CORO2A mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	All	1.000	0.847	.017	42	view →
PDAC	OS	Median	All	0.715	0.441	.004	27	view →
UCEC	OS	Median	All	1.000	0.898	.004	12	view →
CCRCC	DFS	Median	III,IV	0.435	0.716	.029	7	view →
OV	DFS	Median	All	0.839	1.000	.021	4	view →
GBM	DFS	Quartile	All	0.872	0.693	.010	4	view →
LUAD	OS	Quartile	All	1.000	0.909	.025	3	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

CORO2A–COAD (DFS)

Open the COAD breakdown →