CORO1C

Across TCGA pan-cancer cohorts, CORO1C mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CORO1C data layer compared with 23 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher CORO1C mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated CORO1C expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

CCRCC, GBM, and PDAC are the cancer types where CORO1C mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Quartile	III,IV	0.224	0.847	.001	43	view →
GBM	DFS	Tertile	All	0.615	0.838	.009	18	view →
PDAC	DFS	Median	IV	0.214	0.785	.006	12	view →
HNSC	DFS	Quartile	III,IV	0.884	0.604	.022	6	view →
LSCC	DFS	Tertile	All	0.370	0.866	.010	5	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

CORO1C–CCRCC (DFS)

Open the CCRCC breakdown →