CORO1C

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CORO1C mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CORO1C-associated genes across cancer lineages are TAFA1, CENPVL3, and SEL1L2. Each is linked with CORO1C in more than 1 cancer types. Because this analysis shows association rather than direction, both CORO1C-to-partner and partner-to-CORO1C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAFA1 grouped by CORO1C-low versus CORO1C-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CORO1C→partner) and Y-score (partner→CORO1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINETAFA1 →+0.329+4.688<.001<.00131
LARGE_INTESTINECENPVL3 →+0.322+3.920<.001.00531
BLOOD_LymphomaSEL1L2 →+0.033+5.643<.001.00231
BLOOD_LymphomaGP9 →+0.494+4.867<.001.00931
BLOOD_LymphomaMYMK →+0.034+5.209.001.00531
Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

TAFA1 by CORO1C expression — LARGE_INTESTINE

Box plot of TAFA1 in CORO1C-low vs CORO1C-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration