CORO1B

Across TCGA pan-cancer cohorts, CORO1B Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated CORO1B data layer compared with 21 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher CORO1B Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CORO1B expression acts as an unfavorable survival marker, although some lineages such as BLCA show a favorable association.

KIRC, PRAD, and BLCA are the cancer types where CORO1B Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.138	0.655	.019	10	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
BLCA	DFS	Median	II,III,IV	1.000	0.329	.042	4	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

CORO1B–KIRC (OS)

Open the KIRC breakdown →