CORO1B

Across TCGA patient cohorts, CORO1B mutation is significantly associated with the RNA expression of many other genes, with 194 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CORO1B-associated genes across cancer lineages are ALDH7A1P4, MIR4253, and OR8B1P. Each is linked with CORO1B in more than 2 cancer types. Because this analysis shows association rather than direction, both CORO1B-to-partner and partner-to-CORO1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ALDH7A1P4 grouped by CORO1B-low versus CORO1B-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CORO1B→partner) and Y-score (partner→CORO1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ALDH7A1P4 →	+0.130	+4.584	<.001	.005	3	3
COAD	MIR4253 →	+0.957	+4.384	<.001	.006	3	3
LUAD	OR8B1P →	+0.040	+5.108	<.001	.002	3	2
CESC	HSPA8P13 →	+0.081	+5.144	.003	.003	3	2
CESC	TRIM64EP →	+0.025	+4.969	<.001	.004	3	2
BLCA	VN1R35P →	+0.225	+4.266	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 194 associations by consensus.

ALDH7A1P4 by CORO1B expression — LUAD

Explore this box plot interactively →