CORO1B

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CORO1B mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. KIRP shows the largest number of these associations.

The most reproducible CORO1B-associated genes across cancer lineages are Tregs, Macrophages, and Basophils. Each is linked with CORO1B in more than 1 cancer types. Because this analysis shows association rather than direction, both CORO1B-to-partner and partner-to-CORO1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Tregs grouped by CORO1B-low versus CORO1B-high in KIRP.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CORO1B→partner) and Y-score (partner→CORO1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
KIRPTregs →+0.137+4.023<.001.03232
COADMacrophages →+0.022+3.288.048.04131
UCECBasophils →+0.206+3.000.020.03631
KIRPCD4+ Tcm →+0.072+4.023<.001.03231
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Tregs by CORO1B expression — KIRP

Box plot of Tregs in CORO1B-low vs CORO1B-high samples in KIRP.

Explore this box plot interactively →

Exploration