CORO1B

Across TCGA cell cohorts, CORO1B mutation is significantly associated with the RNA expression of many other genes, with 64 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CORO1B-associated genes across cancer lineages are SLC5A4, PHOX2B, and BHLHE23. Each is linked with CORO1B in more than 1 cancer types. Because this analysis shows association rather than direction, both CORO1B-to-partner and partner-to-CORO1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC5A4 grouped by CORO1B-low versus CORO1B-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CORO1B→partner) and Y-score (partner→CORO1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SLC5A4 →	+0.361	+4.471	<.001	.001	3	1
BLOOD_Leukemia	PHOX2B →	+0.021	+4.365	<.001	.002	3	1
BLOOD_Leukemia	BHLHE23 →	+1.468	+3.691	<.001	.005	3	1
BLOOD_Leukemia	BRDT →	+0.136	+3.342	<.001	.006	3	1
BLOOD_Leukemia	CD1B →	+4.820	+3.619	<.001	.007	3	1
BLOOD_Leukemia	DIRAS2 →	+0.102	+3.551	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 64 associations by consensus.

SLC5A4 by CORO1B expression — BLOOD_Leukemia

Explore this box plot interactively →